NiftyFit has been made available as a joint publication and software release. This software incorporates model-fitting functionality for the estimation of microstructural and microvascular characteristics from diffusion-weighted imaging (Zach), blood perfusion and cerebral blood flow from ASL (David) and T1 relaxometry, and g-ratio measurement from diffusion and T2 relaxometry (part of the Preterm Imaging Project). In future it will be extended to functional connectivity measurement from fMRI (Michael). Quantitative measurements made by the fitting are relevant for diagnosis, estimation of disease progression, and the monitoring of disease-modifying treatments and the software has already supported a number of existing publications.