NiftyRec is a software package for fully 3D Stochastic Emission Tomographic Reconstruction. The package includes a Matlab Toolbox with inline documentation and a library for C/C++ development. Computationally intensive tasks have a GPU implementation based on CUDA. Currently MLEM, OSEM, and OSL-MAPEM reconstruction algorithms are supported. Contributors include Stefano Pedemonte, and Sebastien Ourselin.