Filled Vacancies

4-year studentship project including MRes and PHD Funding 

Studentship to commence at start of Academic Year 2015-16

 

Non-Clinical Supervisor: Dr Andre Altmann
Clinical Supervisor: Dr Jonathan Rohrer

 

Dementia is a broad category of brain disorders that cause long term and often gradual decrease in the ability to think and function normally in daily life. The probably most well-known member of this disease category is Alzheimer’s disorder, which is characterized by loss of memory. Currently about 850,000 people are living with dementia in the UK and the number is projected to increase to 2 million by 2050. There is currently no treatment to delay or forestall the course of Alzheimer’s disease or any other dementia. The second most prevalent form of dementia is frontotemporal dementia - causing changes in social and personal behavior, apathy, blunting of emotions, and deficits in both expressive and receptive language.

Dementias are disorders of the brain and as such are studied using neuroimaging methodologies to visualize and track the changes that occur in order to better understand the disease process. While the major risk factor for developing any kind of dementia is advanced age, there is a substantial genetic component as well. The aim of this PhD is to develop statistical methods in order to combine multiple neuroimaging modalities with high dimensional genetic information to better understand the molecular genetic underpinnings of Alzheimer’s disease and frontotemporal dementia.

 

The successful candidate will have access to a number of large cohorts providing both types of data: neuroimaging and genetics. Examples are the ADNI (Alzheimer’s disease neuroimaging) dataset with close to 2,000 subjects and the UK biobank comprising 0.5 mio subjects (about 5,000 with imaging data).

 

Eligibility and to apply:

In order to be eligible, applicants will have achieved (or are predicted) a first class or upper second class honours undergraduate degree (or equivalent international qualifications or experience) in a related subject. The studentship compromises of UK/EU fees level and a tax-free stipend of £16,851 per annum. In order to qualify candidates must be UK/EU passport holders or qualify for UCL home fees status.

To apply please send:

1) A copy of your CV

2) Contact details of 2 academic references

3) A cover letter stating the reasons you are applying for this studentship to: applications@medphys.ucl.ac.uk

 

Closing Date: Tue 25 August 2015