Filled Vacancies


Department: Medical Physics and Bioengineering
Subsection: Translational Imaging Group (TIG) within the Centre for Medical Imaging Computing (CMIC)
Duration: 3 years
Stipend: £16,851 per annum tax-free, full fees paid.

Closing Date for Applications: July 10th, 2015

Project Outline:


Applications are invited for a PhD studentship based within the UCL Translational Imaging Group, Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering in conjunction with the UCL Institute of Neurology, Department of Brain Repair & Rehabilitation, starting in October 2015.


Cerebrovascular disease is an umbrella term for diseases that affect the blood vessels supplying the brain. Different medical conditions, such as hypertension, cause permanent changes in the architecture of the blood vessels making them narrow, stiff, deformed, uneven and more vulnerable to fluctuations in blood pressure. These architectural changes can lead to ischemic stroke, caused by a reduction in blood flow due to narrowing blood vessels, or haemorrhagic stroke, caused by the tearing of the blood vessel wall.


Imaging modalities, such as computed tomography angiogram (CTA) or time of flight MRI angiography (TOF-MRI) provide detailed pictures of the cerebral blood vessels and vascular tree. In current clinical practice, radiologists visually inspect these images (detecting the presence of a blockage, and studying the shape, size and tortuosity of the vascular tree) in order to diagnose these cerebrovascular conditions. The aim of this PhD is to develop novel algorithms to extract, parameterise and quantify the morphological properties of the vascular tree, improving our ability to detect, predict and understand cerebrovascular pathology.
The successful candidate will have access to a very large clinical database of CTA data (5000+ subjects) from stroke patients and TOF-MRI data from a cerebrovascular clinical trial (300+ subjects). The main methodological developments will include segmentation of the vascular tree, parameterization of the vessel wall, and characterization of the vessel properties (e.g. shape, tortuosity, stenosis).


Eligibility and to apply:
In order to be eligible, applicants will have achieved (or are predicted) a first class or upper second class honours undergraduate degree (or equivalent international qualifications or experience) in a related subject.


The studentship compromises of UK/EU fees level and a tax-free stipend of £16,851 per annum. In order to qualify candidates must be UK/EU passport holders or qualify for UCL home fees status.



To apply please send:
1) A copy of your CV


2) Contact details of 2 academic references


3) A cover letter stating the reasons you are applying for this studentship



Further Details


If you have any queries regarding the scientific content of the vacancy please contact Dr M. Jorge Cardoso or Prof Seb Ourselin For general application queries please contact Ms Neha Shah (