NiftyFit has been made available as a joint publication and software release. This software incorporates model-fitting functionality for the estimation of microstructural and microvascular characteristics from diffusion-weighted imaging (Zach), blood perfusion and cerebral blood flow from ASL (David) and T1 relaxometry, and g-ratio measurement from diffusion and T2 relaxometry (part of the Preterm Imaging Project). In future it will be extended to functional connectivity measurement from fMRI (Michael). Quantitative measurements made by the fitting are relevant for diagnosis, estimation of disease progression, and the monitoring of disease-modifying treatments and the software has already supported a number of existing publications.

Jorge will be 9th winner of the prize, which is awarded annually by the UCL Centre for Neuroimaging Techniques

His work is based mostly on the concept of information propagation, with an emphasis on the Geodesic Information Flow (GIF) algorithm. which is able to provide a coherent picture of human anatomy and change. Segmentations obtained from GIF have been shown to improve the accuracy and power of ROI-based imaging biomarkers in large scale clinical studies, and enabling the estimation of improved microstructural characteristics from diffusion imaging, functional connectivity from fMRI, and blood perfusion and cerebral blood flow from ASL. These biomarkers are relevant for diagnosis, estimation of disease progression, and the monitoring of disease-modifying treatments.

Congratulations to Jorge for his achievements!




We are pleased to announce that Dr. Juan Eugenio Iglesias is joining the Translational Imaging Group at UCL. Dr. Iglesias has been awarded a Starting Grant from the European Research Council titled “Building Next-Generation Computational Tools for High Resolution Neuroimaging Studies”. The goal of this project is to build a set of computational tools that will enable neuroimaging studies to take full advantage of the increased resolution of modern MR technology. Other research interests of Dr. Iglesias’s include shape models and discriminative techniques for medical image segmentation.

New review paper in The Lancet: Neurology on "Brain imaging in the assessment for epilepsy surgery", available online here.


Duncan, John S;  Winston,Gavin P; Koepp, Matthias J; Ourselin, Sebastien, "Brain imaging in the assessment for epilepsy surgery", The Lancet: Neurology (2016)


Dr. Christos Bergeles from TIG will be presenting his work on microsurgical robots for vitreoretinal interventions at the 100% Optical Event at Excel London on Monday 8th February. He was invited as a member of the Speaker Network from Fight for Sight.


100% Optical is a premier EU event around ophthalmology and optometry, and attracts several thousand of participants from industry, clinic, and research.

ismrm.pngTIG has had 23 pieces of work accepted for this years ISMRM in Singapore (May 7th-13th) including five oral presentations. We look forward to presenting this work at the conference in May.

MRM journal paper accepted and now available online here. By Sjoerd Vos, C.M.W. Tax, P.R. Luijten, S. Ourselin, A. Leemans, M. Froeling

EpiNavTrajPlannerThe Wellcome Trust have awarded a multi-million pound grant through the Health Innovation Challenge Fund to continue research into Image-guided neurosurgical treatment of epilepsy. The work is led by Professor John Duncan and Professor Sebastien Ourselin.